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Stem Cell Res ; 41: 101640, 2019 12.
Article En | MEDLINE | ID: mdl-31710912

We describe generation of human induced pluripotent stem cell (hiPSC) lines of three unrelated idiopathic late onset Parkinson disease patients and two healthy controls above 60 years of age without neurological diseases nor Ashkenazi ancestry. Human iPSC were derived from peripheral blood-erythroblasts using integration free episomal plasmids carrying four reprogramming factors OCT4, SOX2, c-MYC, KLF4 and BCL-XL. The hiPSC lines were characterized according to established criteria.


Cell Culture Techniques/methods , Cell Line/pathology , Induced Pluripotent Stem Cells/pathology , Parkinson Disease/pathology , Aged , Base Sequence , Humans , Kruppel-Like Factor 4 , Middle Aged , Reproducibility of Results
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